BEL Tutorial

BEL Tutorial

 

R. Brett Fields, M.S.

The Introduction to BEL webinar provides an overview of the Biological Expression Language (BEL) format and how it has been applied to construct a large array of biological networks that will be reviewed during the NVC. Unique features of BEL are highlighted in relation to other prominent languages commonly utilized for network building. The foundation of language architecture is reviewed using specific examples derived from the NVC website and the array of visualization styles utilized for language representation within networks are highlighted. Construction of BEL statements, which form the basis of node:edge relationships in the networks, is reviewed in detail to provide users an overview of language mechanics that will facilitate proper edge review during the NVC. In addition, users are provided a step-by-step guided tutorial on adding new edge evidence(s) and new edge relationships to the existing biological networks where appropriate. The webinar will incorporate a live demonstration and question-answer session to address specific questions provided by the audience.

About the Speaker

Brett has been a team member at Selventa since June 2012, during which time he served an instrumental role in constructing the series of human biological networks being reviewed during the Network Verification Challenge. During network construction, he contributed extensively to the analysis of lung-specific microarray data sets in the public domain to enhance the networks with features present in Chronic Obstructive Pulmonary Disease (COPD). His scientific expertise in immunology contributed greatly to the refinement of network architecture, particularly related to networks within the inflammation track presented on the NVC website. Brett received his Bachelor of Science (B.S.) degree in Biochemistry from The Georgia Institute of Technology in Atlanta, GA and received a Master of Science (M.S.) degree in Cellular Biology from The Scripps Research Institute in La Jolla, CA.

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